Combination cytokine therapy: The next generation of rheumatoid arthritis therapy?
نویسندگان
چکیده
منابع مشابه
Combination therapy in rheumatoid arthritis.
It has become clear that early suppression of rheumatoid arthritis disease activity is important in preventing progressive joint destruction and functional decline. To achieve this goal, many rheumatologists today advocate a more aggressive approach, using combinations of classic disease-modifying antirheumatic drugs-often including methotrexate-or new drugs. During the last 2 years, the combin...
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WHILE the treatment of RA has become more aggressive in recent years by the earlier use of second-line agents, remissions, as measured by the ACR [1], resulting from these therapies are rare. Concern has been expressed that the mortality risk in patients with RA is similar to that seen in Stage IV Hodgkin's disease or three vessel coronary artery disease [2]. Certainly, the consideration of dis...
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approaches needs to be considered; triple therapy has been reported to be well tolerated at three to five years, while similar data are not available for methotrexate and cyclosporin A. The success of combination DMARD therapy in recent double blind controlled studies is encouraging.2223 As is frequently the case, however, the success of these approaches raises as many questions as it answers. ...
متن کاملCombination therapy with cyclosporin in rheumatoid arthritis.
The role of combination therapy in rheumatoid arthritis (RA) is increasing with the development of new treatment modalities. Past combinations of slow-acting anti-rheumatic drugs resulted in either excessive side-effects or lack of efficacy over single-agent therapy. However, refined methodology and a better understanding of the mechanism of action of newer agents have led to improved combinati...
متن کاملThe Effect of Acceptance and Commitment Therapy on Muscle Pain in Patients with Rheumatoid Arthritis
Introduction: Rheumatoid arthritis is an autoimmune and inflammatory disease that can cause chronic pain. The aim of this study was to investigate the effect of acceptance and commitment therapy on muscle pain in patients with rheumatoid arthritis. Material & Methods: This research was a Quasi-experimental design with experimental and control groups. The study population consisted of 245 patien...
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ژورنال
عنوان ژورنال: Arthritis & Rheumatism
سال: 2002
ISSN: 0004-3591,1529-0131
DOI: 10.1002/art1.10158